How does stem cell therapy help with Peripheral Vascular Disease (PVD)?

Autologous fat-derived stem cells secrete essential growth factors that stimulate angiogenesis—the formation of new blood vessels—helping bypass blocked arteries, restore circulation, and deliver oxygen to ischemic limbs.

How are stem cells deployed for non-healing diabetic and vascular ulcers?

We utilize a dual-deployment protocol combining systemic intravenous (IV) infusion with direct micro-injections into the healthy tissue surrounding the wound bed to accelerate local tissue repair and collateral vessel growth.

Can stem cell therapy help prevent amputation in severe vascular disease?

By promoting microvascular regeneration and wound closure in chronic ischemic tissue, stem cell therapy aims to improve peripheral blood flow and support limb salvage strategies alongside conventional vascular care.

What is the cost of stem cell treatment for vascular diseases in Dallas?

Our transparent, all-inclusive treatment package is $16,500. This covers candidate evaluation, cell harvesting, deployment of your own fat-derived cells by IV and local injections (typically 100 million or even more; counts may vary), complimentary hotel stays for out-of-town patients, and follow-ups.

Stem Cell Therapy for Vascular Disease, PAD, & Ulcers in Dallas, TX

Medically Reviewed by: Dr. Bill Johnson, MD — Founder & Medical Director

🏆 Named a “Top Stem Cell Therapy Treatments Company” by Life Sciences Review (2025, 2026)

🩸 Clinical Focus: Stimulating natural collateral angiogenesis and tissue regeneration using your own fat-derived stem cells (typically 100 million or even more; counts may vary).

Understanding Vascular Diseases & Ischemic Tissue Loss

Vascular diseases affect the blood vessels; the arteries and veins that carry blood, oxygen, and other nutrients throughout the body. Vascular diseases include coronary artery disease, aortic disease, varicose veins, and peripheral artery disease, a condition that affects the arteries of the limbs, abdomen, head, and neck. Some health factors contribute to the development of vascular diseases, such as high blood pressure, high cholesterol, diabetes, and obesity. Behavioral factors also contribute to the condition, like smoking, stress, and a sedentary lifestyle. Inflammation and the buildup of cholesterol and fatty deposits in the blood vessels lead to vascular diseases. People with untreated vascular diseases are at risk of blood clots, stroke, heart attack, amputations, and skin ulcers. Vascular complications and impaired microcirculation frequently overlap with systemic autoimmune disorders treated in our Autoimmune & Immune Recovery Center

How Your Own Fat-Derived Cells May Stimulate Angiogenesis

Chronic vascular restriction—whether caused by peripheral artery disease (PAD), microvascular damage, or non-healing diabetic ulcers—deprives tissues of essential oxygen and nutrient-rich blood. Traditional interventions often focus solely on opening existing major arteries. Regenerative medicine, however, approaches vascular recovery at the cellular level by targeting angiogenesis: the natural biological process of forming new blood vessels.

At Innovations Stem Cell Center, our specialized autologous adipose-derived (fat-derived) protocol isolates high yields of Stromal Vascular Fraction (SVF), typically delivering 100 million viable Mesenchymal Stem Cells (MSCs) or even more (counts may vary) in a single treatment session. This massive cellular concentration initiates vascular restoration through three primary biological mechanisms:

1. Secretion of Vascular Growth Factors: Adipose-derived MSCs function as powerful cellular engines, releasing high concentrations of essential signaling proteins—including Vascular Endothelial Growth Factor (VEGF), Basic Fibroblast Growth Factor (bFGF), and Hepatocyte Growth Factor (HGF). These growth factors signal your body to build new collateral capillary networks, bypassing blocked or calcified vessels.
2. Endothelial & Vascular Repair: Mesenchymal stem cells migrate directly to sites of ischemic vascular injury. Once homed to damaged tissue, they interact with local endothelial cells (the inner lining of blood vessels) to promote microvascular repair, reduce arterial inflammation, and reinforce vascular wall structural integrity.
3. Targeted Wound Bed Regeneration: For patients suffering from non-healing diabetic or vascular ulcers, restricted microcirculation prevents standard immune cells and oxygen from reaching the wound. By deploying typically 100 million stem cells or even more (counts may vary) both systemically (via IV infusion) and through targeted micro-injections surrounding the ulcer, the cells stimulate localized capillary sprouting, improve tissue perfusion, and accelerate chronic wound closure.

By harvesting high-yield stem cells directly from your own adipose tissue, our IRB-reviewed procedure provides a safe, domestic, and non-surgical approach to restoring peripheral blood flow and supporting long-term limb health—without the rejection risks associated with donor cells or low-yield bone marrow alternatives.

Frequently Asked Questions

Q: What is Peripheral Vascular Disease?

A: Peripheral vascular disease (PVD) is a disorder of the circulatory system that causes arteries to narrow. The primary cause of peripheral vascular disease is arteriosclerosis or the hardening of the arteries. Blood vessel spasms can also contribute to the condition. Symptoms of the condition cause pain and tiredness in the legs, especially during and after physical activity. PVD typically causes pain and fatigue, often in the legs, and especially during exercise. The pain usually improves with rest. Patients with this circulatory system disorder are at risk of developing blood clots and damage to limbs and extremities. Ulcers can also develop due to poor blood flow to the area.

Q: How Do Stem Cells for Peripheral Vascular Disease Work?

Conditions We Treat with Autologous SVF Protocols

Stem Cell Therapy for Peripheral Vascular Disease

A: Innovations Stem Cell Center treats peripheral vascular disease with stem cell therapy procedures through IV deployment and injections into the locally damaged tissue. Stem cells from fat are highly effective at stimulating the growth of new blood vessels. Once the stem cells have been deployed, they immediately go to work stimulating new blood vessels and helping to heal damaged tissue. The stem cells repair damaged tissues just like they do in other areas of the body damaged by disease or injury- by regenerating cells to heal tissue and using growth factors that promote healing. See our blog Understanding Adipose-Derived Stem Cells

Q: Diabetic Ulcers

A: Diabetic ulcers are a common complication of diabetes. In fact, they are the leading cause of hospitalizations for diabetics in the United States. Diabetic ulcers develop on the feet as a result of diabetes affecting the nerves and blood vessels. They form when skin tissue breaks down and exposes the tissue below. They can be extremely painful and can cause patients discomfort when walking. However, in patients with neuropathy, they may not hurt at all. Diabetic ulcers can become infected, and lead to amputation if not treated. Signs of diabetic ulcers include irritation, swelling, redness, and odors from affected areas. Some patients experience fluid leaking from ulcer sites onto shoes or socks. Serious cases of diabetic ulcers have areas of black tissue that indicate the death of tissue because of infection. Diabetic ulcers are hard to treat and may involve antibiotic therapy and keeping the wound clean and dry. Some diabetic ulcers are so severe they may lead to amputation.

Q: How Do Stem Cells for Diabetic Ulcers Work?

Stem Cell Therapy for Diabetic Ulcers

A: Innovations Stem Cell Center treats diabetic ulcers with stem cell therapy procedure through IV and injection into the tissue around the ulcer. Once the stem cells have been deployed, they immediately go to work to heal damaged tissue. Stem cells from fat are also highly effective at stimulating new blood vessels to form. Once deployed, the stem cells repair damaged tissues just like they do in other areas of the body damaged by disease or injury- by regenerating cells to heal tissue and using growth factors that promote healing. The stem cells also help form new blood vessels and repair nerves which further helps improve the ulcer. Stem cells can be limb saving for some patients with diabetic ulcer disease. Understanding Adipose-Derived Stem Cells

Q: What are Vascular Ulcers?

A: Vascular ulcers are very common in patients over the age of 65, and develop in the lower extremities and leave patients at risk for infection and amputation. Vascular ulcers develop because of peripheral vascular diseases when blood flow to the extremities is restricted and tissues die off. Other causes of vascular ulcers include age and obesity. Vascular ulcers can recur or become chronic, leaving patients in pain and limiting their activities. Treatments for vascular ulcers include compression therapy and working to improve circulation to prevent future ulcers from forming.

Q: How Do Stem Cells for Vascular Ulcers Work?

Stem Cell Therapy for Vascular Ulcers

A: Innovations Stem Cell Center treats vascular ulcers with stem cell therapy through IV and injection into the tissues around the ulcer. Once the stem cells have been deployed, they immediately go to work to heal damaged tissue. The stem cells repair damaged tissues just like they do in other areas of the body damaged by disease or injury- by regenerating cells to heal tissue and using growth factors that promote healing. Stem cells also help to stimulate the development of new blood vessels to help treat the underlying problem. See our blog Understanding Adipose-Derived Stem Cells

Dual-Deployment: Intravenous (IV) & Direct Local Injections

Cost of Stem Cell Treatments

We typically get 100 million cells or even more (counts may vary), compared with roughly 100,000 from bone marrow. $16,500 for initial treatment Your investment includes: ✅ Complete medical evaluation ✅ Stem cell harvest & processing ✅ IV infusion + local injections ✅ Follow-up care included Second treatment (if needed): $10,000 Financing is available. Contact us directly and we’ll help you apply. For more reading on Stem Cells read our blog What are Stem Cells?. Innovations Medical offers stem cell treatment procedures at our Dallas practice location. Call our office at (972) 893-9849 to schedule a consultation.

Comprehensive Support for Out-of-State Patients

Traveling to Dallas for vascular evaluation or non-healing ulcer treatment? Review our Patient Travel Package & Perks for complimentary hotel details.